Direct enantioseparation of 1-(2-hydroxyphenyl) ethylamines via diastereomeric salt formation: Chiral recognition mechanism based on the crystal structure

DOI: 10.1039/c4ra00414k

Source and publish data:

RSC Advances p. 25609 - 25615 (2014)

Update date:2022-07-29

Topics:

Authors:

Kodama, Koichi

Hayashi, Naoki

Fujita, Mikidai

Hirose, Takuji

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c4ra00414k

In this study, the direct enantioseparation of unprotected 1-(2-hydroxyphenyl)ethylamines (1a and 1b) via diastereomeric salt formation is reported. After the one-pot synthesis of racemic 1, the screening of seven acidic chiral resolving agents showed tha

Full text of DOI:10.1039/c4ra00414k

Products guided by the article

Product name:rac-1-(2-hydroxy-3,5-di-tert-butylphenyl)ethylamine

Cas No:1273663-33-4

R&D Labs maybe for 1273663-33-4

X.T.Y Environ-Tech Co.,Ltd

Contact:+86-310-7092106

Address:Quzhou Modern & New Industrial Park, Handan, Hebei 057250, China
Jinan Jinguilin Chemical Co.,Ltd

Contact:+86-531-81188412

Address:3rd floor of Torch Building, Huanyuan Rd, City of Jinan
Chengdu Yunyi International Trade Co., Ltd

Contact:

Address:china
Pengchen New Material Technology Co., Ltd.

Contact:+86-512-63680537

Address:99.6 km of national road 318, Meiyan Community,Pingwang Town, Wujiang District, Suzhou 215225
Tomo Pharma Chem Co., Limited

Contact:+86-158-05817090

Address:ROOM 9F, FLAT 2, GUODU DEVELOPING BLDG, No.182, ZHAOHUI ROAD

Relevant to this article

Iodine-mediated oxidative Pictet-Spengler reaction using terminal alkyne as the 2-oxoaldehyde surrogate for the synthesis of 1-aroyl-β-carbolines and fused-nitrogen heterocycles

Doi:10.1016/j.tet.2017.03.031
(2017)
2-(Fluoro-) and 2-(methoxyanilino)-1,4-naphthoquinones. Synthesis and mechanism and effect of fluorine substitution on redox reactivity and NMR

Doi:10.1016/j.jfluchem.2015.08.016
(2015)
A practical optical resolution of (arylsulfinyl)acetones and its application to the synthesis of 2-(arylsulfinyl)cycloalkanones

Doi:10.1246/bcsj.62.3531
(1989)
A new synthetic route to P-chiral phosphine-boranes of high enantiopurity via stereocontrolled Pd(0)-Cu(I) cocatalyzed aromatic phosphorylation

Doi:10.1021/jo0003605
(2000)
Diastereoselection in reactions of pinanediol dichloromethaneboronate

Doi:10.1021/om50005a010
(1983)
Generation and Reactions of the Dianion of 3-Hydroxy-5-methylisoxazole, a Covenient β-Keto Amide Sython. Total Synthesis of Muscimol

Doi:10.1021/jo00171a030
(1983)

Article Doi