The Stereoselectivity of the Alkylation of the Dianion of Ethyl 2-Hydroxy-6-methylcyclohexanecarboxylates: Control of Stereochemistry at Three Adjacent Stereogenic Centers

DOI: 10.1002/hlca.19890720821

Source and publish data:

Helvetica Chimica Acta p. 1846 - 1851 (1989)

Update date:2022-07-29

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Authors:

Frater, Georg

Guenther, Wulf

Mueller, Urs

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Article abstract of DOI:10.1002/hlca.19890720821

Yeast reduction of rac-ethyl 2-methyl-6-oxocyclohexanecarboxylate (rac-1) yielded selectively (+)-ethyl 2-hydroxy-6-methylcyclohexane carboxylate (+)-2 (Scheme 1) which has been alkylated with 5-iodo-2-methylbut-2-ene by the dianion method to furnish the

Full text of DOI:10.1002/hlca.19890720821

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