A Annulation Approach to Nitrogen Heterocycles Using 2,3-Bis(phenylsulfonyl)-1,3-butadiene and Primary Amines

Article abstract of DOI:10.1021/jo00303a009

The reaction of amines with 2,3-bis(phenylsulfonyl)-1,3-butadiene affords pyrrolidines in high yield.The formation of nitrogen heterocycle involves initial conjugate addition and this is followed by a 5-endo-trig cyclization of the resulting amine onto th