A facile method for hydroxytrifluoromethylation of alkenes with Langlois reagent and DMSO

DOI: 10.1039/c9gc00886a

Source and publish data:

Green Chemistry p. 2983 - 2987 (2019)

Update date:2022-08-03

Topics:

Authors:

Shen, Wei-Guo

Wu, Qing-Yan

Gong, Xing-Yu

Ao, Gui-Zhen

Liu, Feng

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c9gc00886a

A practical hydroxytrifluoromethylation of alkenes using the Langlois reagent as the trifluoromethyl source and DMSO as the oxidant is described. This reaction is mild and operationally simple, without exclusion of either moisture or oxygen, allowing access to a wide range of β-trifluoromethyl alcohols in useful yields. This transformation is environmentally friendly and can be easily scaled up to gram level.

Full text of DOI:10.1039/c9gc00886a

Products guided by the article

Product name:1-([1,1'-biphenyl]-4-yl)-3,3,3-trifluoropropan-1-ol

Cas No:1282444-70-5

R&D Labs maybe for 1282444-70-5

MS( MAOSHENG )Chemical CO.,LTD

Contact:+86-519-82726678.82726378

Address:TAOXI INDUSTRY ZONE JINTAN
LianYunGang Chiral Chemical(CHINA) CO.,LTD

Contact:+86-518-83616958 +86-519-82884848

Address:LianYunGang Chemical Industry Park (JiangSu)
ANHUI CHEM-BRIGHT BIOENGINEERING CO.,LTD

Contact:86-561-4080321

Address:No.8 Lieshan Industrial Zone of Huaibei
Golden Union Agrochemical Import and Export Co., Ltd.

Contact:86-755-23910527

Address:Room 1106, Tower 3A, Excellence Century Center, Futian District, Shenzhen, China
Hangzhou Eastbiopharm Co.,Ltd.

Contact:+86-571-88931780

Address:Hangzhou,China

Relevant to this article

Studies on Organophosphorus Compounds XL. A One-Pot Procedure for the Mono-O-Alkylation of Phosphonic Acid: A Facile Synthesis of Alkyl Hydrogen p-Substituted Phenylphosphonates

Doi:10.1055/s-1990-26813
(1990)
Synthesis, Structural, Spectroscopic, and Alkali-Metal Cations Complexation Studies of a Bis-Anthracenediyl Macrotricyclic Ditopic Receptor

Doi:10.1021/jo00097a030
(1994)
SYNTHESIS OF MACROHETEROCYCLES - ANALOGS OF DIBENZO-CROWN COMPOUNDS. 4. 15-18-MEMBERED PYRIDINE-CONTAINING CROWN COMPOUNDS

Doi:10.1007/BF00481531
(1989)
Synthesis of 3-aminoindole derivatives: Combination of Thorpe-Ziegler cyclization and unexpected allylindium-mediated decyanation

Doi:10.1016/j.tetlet.2011.01.085
(2011)
Improving optoelectronic properties of the 2,7-polyfluorene derivatives with carbazole and oxadiazole pendants by incorporating the blue-emitting iridium complex pendants in C-9 position of fluorine unit

Doi:10.1002/pola.25017
(2012)
A convenient preparation of p-methoxybenzyl esters

Doi:10.1080/00397910008087040
(2000)

Article Doi