PRACTICAL METHOD FOR SYNTHESIS OF OPTICALLY PURE PROPARGYLIC ALCOHOLS

DOI: 10.1016/S0040-4039(01)93429-X

Source and publish data:

Tetrahedron Letters p. 7083 - 7086 (1989)

Update date:2022-08-02

Topics:

Authors:

Ito, Takayori

Okamoto, Sentaro

Sato, Fumie

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Article abstract of DOI:10.1016/S0040-4039(01)93429-X

Highly efficient practical method for synthesis of optically pure propargylic alcohols is described which involves the synthesis of chiral γ-iodo allylic alcohols by the Sharpless kinetic resolution of secondary γ-hetero substituted allylic alcohols and their 1,2-dehydrohalogenation reaction.

Full text of DOI:10.1016/S0040-4039(01)93429-X

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