Dinucleotide-analogous tetrapeptides. Specific triplex formation with complementary polynucleotides

DOI: 10.1016/S0040-4039(97)10269-6

Source and publish data:

Tetrahedron Letters p. 8363 - 8366 (1997)

Update date:2022-08-05

Topics:

Authors:

Yamazaki, Takahisa

Komatsu, Kazunori

Umemiya, Hiroki

Hashimoto, Yuichi

Shudo, Koichi

Kagechika, Hiroyuki

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Article abstract of DOI:10.1016/S0040-4039(97)10269-6

Several tetrapeptides (1-4) having two adenyl moieties at the side chains interacted complementary base-specifically with poly (dT) or poly (U). The hypochromic effects and CD spectra of the complexes suggested the formation of triplexes, which are more stable than those between natural ApA and the polynucleotides.

Full text of DOI:10.1016/S0040-4039(97)10269-6

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