A new preparation of N-alkyl-2(1H)-pyridones from 2-glycudoxypyridines

Article abstract of DOI:10.1016/0040-4039(91)80463-G

N-Alkyl-2(1H)-pyridones are prepared in high yield by the reaction of 2-glycidoxypyridines with carboxylic acids, phenols or thiophenols. These reactions proceed through an oxazolinium ion intermediate, which reacts with the acid counter ion to give the u