Reagents and methods for the solid-phase synthesis of protein-EDTA for use in affinity cleaving

Article abstract of DOI:10.1021/ja00173a027

Synthetic procedures for the introduction of the metal chelator ethylenediaminetetraacetic acid (EDTA) at unique amino acid positions of proteins by solid-phase methods are described. Two protected derivatives of EDTA compatible with Merrifield solid-phas