Chemical and Pharmaceutical Bulletin p. 842 - 844 (1990)
Update date:2022-08-04
Topics:
Aihara
Higuchi
Hirobe
Several complicated o-methoxyphenols were oxidized with high selectivity to catechols by a Cu2+ - ascorbic acid - O2 system. In this way, the RBL-1 5-lipoxygenase inhibitory activities of o-methoxyphenols were greatly increased. [6]-Norgingerol (4), a novel compound derived from [6]-gingerol (3), shows promise as a lead compound for new drugs because of its high inhibitory potency (IC50 = 5.0 x 10-8 M).
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Doi:10.1016/j.molstruc.2011.01.024
(2011)Doi:10.1016/0008-6215(89)85019-0
(1989)Doi:10.1248/cpb.38.590
(1990)Doi:10.1007/BF00938281
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(1990)Doi:10.1016/0040-4039(90)80105-U
(1990)
