'Dibutyltin diperchlorate' for activation of glycosyl fluoride

Article abstract of DOI:10.1016/0008-6215(93)84059-F

The Bu₂SnCl₂-2AgClO₄ combination shows promise as an activator for glycosyl fluorides, as revealed by experiments with 2,3,4,6-tetra-O-benzyl-α-D-mannosyl fluoride as a model glycosyl donor in comparison with activators prepared in situ from five types of organotin chlorides (Bu₂SnCl₂, Me₂SnCl₂, Bu₃SnCl, Me₃SnCl, and Ph₃SnCl) in combination with silver perchlorate. The Bu₂SnCl₂-2AgClO₄ combination shows promise as an activator for glycosyl fluorides, as revealed by experiments with 2, 3,4,6-tetra-O-benzyl-α-D-mannosyl fluoride as a model glycosyl donor in comparison with activators prepared in situ from five types of organotin chlorides (Bu₂SnCl₂, Me₂SnCl₂, Bu₃ SnCl, Me₃SnCl, and Ph₃SnCl) in combination with silver perchlorate.