Antirhinovirus structure-activity relationships of 6-substituted-9-(4-methylbenzyl)-2-trifluoromethyl-9H-purines

Article abstract of DOI:10.1016/0223-5234(90)90021-T

To evaluate the effect of different 6-substituents on antirhinoviral activity, a series of 6-substituted-9-(4-methylbenzyl)-2-trifluoromethyl-9H-purines was synthesized and tested.A matrix map of space adjacent to the 6-position was constructed to facilit