Synthesis of cyclic α-amino acids through ring closure of glycine derived free radicals

DOI: 10.1016/S0040-4039(00)94622-7

Source and publish data:

Tetrahedron Letters p. 759 - 762 (1990)

Update date:2022-08-04

Topics:

Authors:

Esch, Peter M.

Hiemstra, Henk

Speckamp, W. Nico

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Article abstract of DOI:10.1016/S0040-4039(00)94622-7

Cyclizations of 1-methoxycarbonyl-2-aza-5-hexenyl (and related) radical intermediates proceed in good yields and constitute a novel synthetic route to proline and pipecolic acid analogues.

Full text of DOI:10.1016/S0040-4039(00)94622-7

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Product name:Acetic acid, [3-butenyl(ethoxycarbonyl)amino](phenylthio)-, methyl ester

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