Synthesis of new [(2S)-N-(p-Tolylsulfonyl)-2-Pyrrolidinyl]Propyl 2,3,4-Tri-O-Acetyl- and 2,3,4-Tri-O-Benzyl-β-L-Fucopyranosides

Article abstract of DOI:10.1515/HC.2010.16.2-3.105

Synthesis of two new glycoheterocyclic compounds, [(2S)-N-(p-tolylsulfonyl) -2-pyrrolidinyl]propyl 2,3,4-tri-O-acetyl- and 2,3,4-tri-O-benzyl-β-L- fucopyranosides la and lb, starting from δ-amino alcohol (-)-[(2S)-N-(ptolylsulfonyl)-2-pyrrolidinyl]propan-l-ol 2 and O-α-L-fucosyltrichloroacetimidates 3a or 3b as glycosyl donor is described. Hitherto δ-aminoalcohol 2 was synthesized from L-proline without any racemization during its preparation.

Full text of DOI:10.1515/HC.2010.16.2-3.105

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Authenticated | 172.16.1.226
Download Date | 7/5/12 5:05 PM

Brought to you by | University of Guelph (University of Guelph)
Authenticated | 172.16.1.226
Download Date | 7/5/12 5:05 PM

Brought to you by | University of Guelph (University of Guelph)
Authenticated | 172.16.1.226
Download Date | 7/5/12 5:05 PM

Brought to you by | University of Guelph (University of Guelph)
Authenticated | 172.16.1.226
Download Date | 7/5/12 5:05 PM

Brought to you by | University of Guelph (University of Guelph)
Authenticated | 172.16.1.226
Download Date | 7/5/12 5:05 PM

Brought to you by | University of Guelph (University of Guelph)
Authenticated | 172.16.1.226
Download Date | 7/5/12 5:05 PM

Brought to you by | University of Guelph (University of Guelph)
Authenticated | 172.16.1.226
Download Date | 7/5/12 5:05 PM

Brought to you by | University of Guelph (University of Guelph)
Authenticated | 172.16.1.226
Download Date | 7/5/12 5:05 PM