An Unusual Base-Mediated Cyclization of Ketimines Derived from 2-(Trifluoromethyl)aniline That Involves the Trifluoromethyl Group: An Expedient Route to 2-Arylquinolines

DOI: 10.1021/jo00303a001

Source and publish data:

Journal of Organic Chemistry p. 4777 - 4779 (1990)

Update date:2022-07-29

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Authors:

Strekowski, Lucjan

Wydra, Roman L.

Cegla, Marek T.

Czarny, Agnieszka

Harden, Donald B.

et al. et al.

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Article abstract of DOI:10.1021/jo00303a001

6-(Substituted methylene)-N-(arylalkylidene)-2,4-cyclohexadien-1-imines, such as 13, 17, and 21 (Scheme II) are suggested intermediates in a novel synthetic route to 2-arylquinolines based on the reaction of trifluoromethyl-substituted ketimines, such as

Full text of DOI:10.1021/jo00303a001

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