Acetazolamide-like carbonic anhydrase inhibitors with topical ocular hypotensive activity

DOI: 10.1021/jm00092a021

Source and publish data:

Journal of Medicinal Chemistry p. 2697 - 2703 (1992)

Update date:2022-07-29

Topics:

Authors:

Antonaroli

Bianco Bianco

Brufani Brufani

Cellai Cellai

Lo Baido

Potier Potier

Bonomi Bonomi

Perfetti

Fiaschi Fiaschi

Segre Segre

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00092a021

New carbonic anhydrase (EC 4.2.1.1) inhibitors were synthesized as potential drugs for the topical treatment of glaucoma. They were obtained by substituting the acetyl group of acetazolamide and methazolamide with bicarboxylic acids of different chain len

Full text of DOI:10.1021/jm00092a021

Products guided by the article

Product name:Butanoic acid, 4-oxo-4-[[5-[(phenylmethyl)thio]-1,3,4-thiadiazol-2-yl]amino]-, pentyl ester

Cas No:129504-23-0

R&D Labs maybe for 129504-23-0

Rayfull Holding Co., Ltd

Contact:+86-577-65618087-605

Address:Room 402, Unit 4 Xinhu Bldg. Waitan Ruian City, Zhejiang China.
Shanghai Mintchem Development ., Ltd

Contact:0086 21 5190 8570

Address:R602,4#,89Nong, Mudan Road Pudong Shanghai China
Suzhou CarbonWell Pharma-Tech Co., Ltd

Contact:Tel: + 86 (0)512-8898-1216; + 86-18606258602

Address:2358 Changan Road, Wujiang Scientific Innovation Park, Wujiang, Jiangsu Province, P. R. China 215200
Guangzhou Flower's Song Fine Chemical CO,. Ltd

Contact:+86-20-87475199

Address:No.12, Fenghuang 3 Road, Jiulong Industrial Park, Luogang District, Guangzhou. China
shandong zhongke taidou chemical co.,ltd

Contact:86-531-88682301

Address:Jinan shandong Province CHina

Relevant to this article

Biscyclophanes. Part 1: Synthesis of a Common-nuclear Bis<1.1.1>orthocyclophane, First Member of a New Family of Cyclophanes

Doi:10.1039/P19920000881
(1992)
Fluorescent naphthalene-based benzene tripod for selective recognition of fluoride in physiological condition

Doi:10.1007/s12039-015-0779-0
(2015)
Unique Stereocontrol in Lanthanide(III)-Catalyzed Aldol Reactions with the Ketene Silyl Acetal of Methyl (R)-3-Hydroxybutanoate

Doi:10.1016/S0040-4039(00)91648-4
(1992)
Stereoselective synthesis of N-acetyl-L-tolyposamine from (S) ethyl β-hydroxybutyrate

Doi:10.1016/0040-4039(92)88182-5
(1992)
The donor-stabilized silylene bis[N,N′-diisopropylbenzamidinato(-)] silicon(II): Synthesis, electronic structure, and reactivity

Doi:10.1002/chem.201402483
(2014)
Lanthanum triflate-triggered synthesis of tetrahydroquinazolinone derivatives of N-allylquinolone and their biological assessment

Doi:10.2298/JSC120121039J
(2012)

Article Doi