Acetazolamide-like carbonic anhydrase inhibitors with topical ocular hypotensive activity

DOI: 10.1021/jm00092a021

Source and publish data:

Journal of Medicinal Chemistry p. 2697 - 2703 (1992)

Update date:2022-07-29

Topics:

Authors:

Antonaroli

Bianco Bianco

Brufani Brufani

Cellai Cellai

Lo Baido

Potier Potier

Bonomi Bonomi

Perfetti

Fiaschi Fiaschi

Segre Segre

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Article abstract of DOI:10.1021/jm00092a021

New carbonic anhydrase (EC 4.2.1.1) inhibitors were synthesized as potential drugs for the topical treatment of glaucoma. They were obtained by substituting the acetyl group of acetazolamide and methazolamide with bicarboxylic acids of different chain len

Full text of DOI:10.1021/jm00092a021

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