SYNTHESIS OF VINCA ALKALOIDS AND RELATED COMPOUNDS XLVIII SYNTHESIS OF (+)-CATHARANTHINE AND (+/-)-ALLOCATHARANTHINE

Article abstract of DOI:10.1016/S0040-4020(01)81977-3

The first synthesis of natural (+)-catharanthine (1) has been achieved in a few steps and in ca. 20 percent overall yield based on indole-3-acetic acid.The isomeric (+/-)-allocatharanthine was also prepared.