Inhibitors of HMG-CoA reductase. Biological effects of A 6-[2-[2-(4-fluoro-3-methylphenyl)-4-substituted cyclohexe-1-en-1-yl]ethenyl]-4-hydroxy-3,4,5,6-tetrahydro-2h-pyran-2-o ne

DOI: 10.1016/0223-5234(92)90095-I

Source and publish data:

European Journal of Medicinal Chemistry p. 735 - 742 (1992)

Update date:2022-08-05

Topics: Anti-Inflammatory Effects Antioxidant Effects Immunomodulation

Authors:

Regan Regan

Bruno Bruno

Gustafson

Amin Amin

Neuenschwander

Perrone Perrone

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Article abstract of DOI:10.1016/0223-5234(92)90095-I

We report on a series of potent inhibitors of HMG-CoA reductase (HMGR) that were designed to examine the biological consequences that result from molecular changes in RG 12561. The introduction of functional groups on the cyclohexene nucleus of RG 12561 a

Full text of DOI:10.1016/0223-5234(92)90095-I

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