Total synthesis of clavamine, insecticidally active compound isolated from venom of Joro spider (Nephila clavata)

DOI: 10.1016/S0040-4020(01)90517-4

Source and publish data:

Tetrahedron p. 3819 - 3822 (1990)

Update date:2022-07-29

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Authors:

Teshima, Tadashi

Matsumoto, Takahiro

Miyagawa, Masaaki

Wakamiya, Tateaki

Shiba, Tetsuo

Narai, Noriko

Yoshioka, Masanori

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Article abstract of DOI:10.1016/S0040-4020(01)90517-4

Clavamine, a new insecticidal toxin isolated from the venom of Joro spider (Nephila clavata) was totally synthesized in order to confirm the proposed structure. In clavamine, a fragment of glycylalanine is inserted in the structure of NSTX-3, a New Guinean spider toxin. The synthesis determined the chemical structure of clavamine unambiguously.

Full text of DOI:10.1016/S0040-4020(01)90517-4

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