Total synthesis of clavamine, insecticidally active compound isolated from venom of Joro spider (Nephila clavata)

DOI: 10.1016/S0040-4020(01)90517-4

Source and publish data:

Tetrahedron p. 3819 - 3822 (1990)

Update date:2022-07-29

Topics:

Authors:

Teshima, Tadashi

Matsumoto, Takahiro

Miyagawa, Masaaki

Wakamiya, Tateaki

Shiba, Tetsuo

Narai, Noriko

Yoshioka, Masanori

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)90517-4

Clavamine, a new insecticidal toxin isolated from the venom of Joro spider (Nephila clavata) was totally synthesized in order to confirm the proposed structure. In clavamine, a fragment of glycylalanine is inserted in the structure of NSTX-3, a New Guinean spider toxin. The synthesis determined the chemical structure of clavamine unambiguously.

Full text of DOI:10.1016/S0040-4020(01)90517-4

Products guided by the article

Product name:[(S)-1-(4-{Benzyloxycarbonyl-[2-(5-{2-[2-(2,4-bis-benzyloxy-phenyl)-acetylamino]-3-carbamoyl-propionylamino}-pentylcarbamoyl)-ethyl]-amino}-butylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester

Cas No:129121-69-3

R&D Labs maybe for 129121-69-3

JIANGXI XINXIN CHEMICAL CO., LTD.

Contact:86-15957176628

Address:INDUSTRY ROAD 1, INDUSTRIAL PARK, HEKOU TOWN,YANSHAN COUNTY, JIANGXI PROVINCE, CHINA
Springchem New Material Technology Co.,Limited

website:http://www.spring-chem.com

Contact:86-21-62885108

Address:602B, Building 1, No. 641, Tianshan Road
TIANJIN NORTH JINHENG CHEMICAL PLANT.

Contact:0086-22-59952083

Address:DongShigu Country In JiXian TianJin China
HANGZHOU TOYOND BIOTECH CO., LTD

Contact:+86-571-86965177

Address:No. 189, Fengqi East Road, Hangzhou, China
KODI CHEMICAL CO., LTD

Contact:021

Address:Pudong

Relevant to this article

Efficient Preparation of Chiral C₂-Symmetrical 2,6,9-Trioxabicyclo<3.3.1>nonanes from Cholesteryl Benzoate

Doi:10.1021/jo961818z
(1997)
Developing potent human uric acid transporter 1 (hURAT1) inhibitors

Doi:10.1021/jm1015022
(2011)
Enantioselective Synthesis of 5-LO Inhibitors Using a Gulofuranose Auxiliary

Doi:10.1016/S0040-4039(00)79952-7
(1994)
High-Throughput Preparation of Optically Active Cyanohydrins Mediated by Lipases

Doi:10.1002/ejoc.201601028
(2016)
Transport of the highly charged myo-Inositol Hexakisphosphate molecule across the red blood cell membrane: A phase transfer and biological study

Doi:10.1016/S0968-0896(02)00162-1
(2002)
Transformation of the non-selective aminocyclohexanol-based Hsp90 inhibitor into a Grp94-seletive scaffold

Doi:10.1021/acschembio.6b00747
(2017)

Article Doi