Total synthesis of clavamine, insecticidally active compound isolated from venom of Joro spider (Nephila clavata)

DOI: 10.1016/S0040-4020(01)90517-4

Source and publish data:

Tetrahedron p. 3819 - 3822 (1990)

Update date:2022-07-29

Topics:

Authors:

Teshima, Tadashi

Matsumoto, Takahiro

Miyagawa, Masaaki

Wakamiya, Tateaki

Shiba, Tetsuo

Narai, Noriko

Yoshioka, Masanori

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)90517-4

Clavamine, a new insecticidal toxin isolated from the venom of Joro spider (Nephila clavata) was totally synthesized in order to confirm the proposed structure. In clavamine, a fragment of glycylalanine is inserted in the structure of NSTX-3, a New Guinean spider toxin. The synthesis determined the chemical structure of clavamine unambiguously.

Full text of DOI:10.1016/S0040-4020(01)90517-4

Products guided by the article

Product name:[(S)-1-(4-{Benzyloxycarbonyl-[2-(5-{2-[2-(2,4-bis-benzyloxy-phenyl)-acetylamino]-3-carbamoyl-propionylamino}-pentylcarbamoyl)-ethyl]-amino}-butylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester

Cas No:129121-69-3

R&D Labs maybe for 129121-69-3

Jiangsu Allyrise Pharmaceutical Co., Ltd.(expird)

Contact:+86-523-86818997

Address:Taizhou,Jiangsu Province,CHINA
Kaiping Genuine Biochemical Pharmaceutical Co.,Ltd.

Contact:+86-750-2881198

Address:No.1, Xinke Road, Shatang Town, Kaiping, Guangdong Province, P.R.China
Shandong Jusage Technology Co.,Ltd.

Contact:86-13406130167

Address:No.20,North Ride No.9 Road, Guangrao Economic Development Zone, Shandong Province
Yancheng Creator Chemical Co., Ltd

Contact:0086-515-88710008 88710068 88710858 88710868

Address:No.21 Renming Road, Longgang Town, Yandu County,Yancheng City
Zhejiang Quzhou Jiancheng Silicone Co., Ltd.(Shanghai Jiancheng Industial and Trade Co, Ltd)

Contact:18957018777 +86-570-3888777

Address:The company production base address： Quzhou City, Zhejiang Province high-tech industrial park Nianhua Road 37

Relevant to this article

Efficient Preparation of Chiral C₂-Symmetrical 2,6,9-Trioxabicyclo<3.3.1>nonanes from Cholesteryl Benzoate

Doi:10.1021/jo961818z
(1997)
Developing potent human uric acid transporter 1 (hURAT1) inhibitors

Doi:10.1021/jm1015022
(2011)
Enantioselective Synthesis of 5-LO Inhibitors Using a Gulofuranose Auxiliary

Doi:10.1016/S0040-4039(00)79952-7
(1994)
High-Throughput Preparation of Optically Active Cyanohydrins Mediated by Lipases

Doi:10.1002/ejoc.201601028
(2016)
Transport of the highly charged myo-Inositol Hexakisphosphate molecule across the red blood cell membrane: A phase transfer and biological study

Doi:10.1016/S0968-0896(02)00162-1
(2002)
Transformation of the non-selective aminocyclohexanol-based Hsp90 inhibitor into a Grp94-seletive scaffold

Doi:10.1021/acschembio.6b00747
(2017)

Article Doi