
Tetrahedron Letters p. 7325 - 7328 (1989)
Update date:2022-07-29
Topics:
Smith, Amos B.III
Empfield, James R.
Vaccaro, Henry A.
An enhanced spiroketalization maneuver permitting equilibration at both the C(8) and C(11) centers of spiroketals 17a,b leads to a more concise and efficient synthesis of phyllanthocin (i.e., 21 steps, 5.6percent overall yield).
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