Chemistry of Heterocyclic Compounds p. 304 - 311 (1990)
Update date:2022-08-05
Topics:
Khlebnikov, A. F.
Kostik, E. I.
Kostikov, R. R.
Bespalov, V. Ya.
Pyridinium dichloromethylides, generated from substituted pyridines and dichlorocarbene, react endo-stereoselectively with dimethyl maleate to give substituted 3,3-dichloro-1,2,3,8a-tetrahydroindolizine-1,2-dicarboxylic acid dimethyl esters; the latter compounds are readily dehydrochlorinated and dehydrogenated to give the corresponding indolizine derivatives.Reaction of 3-substituted pyridines with dichlorocarbene and dimethyl maleate leads predominantly to the formation of 8-substituted indolizines.Cycloaddition of 4-picolinium dichloromethylide to unsymmetrical dipol arophiles occurs regioselectively.The observed selectivity in these reactions is consistent with predictions made on the basis of PMO theory.
View MoreTianjin Bright Future Technology Co., Ltd
Contact:0086-22-58016666
Address:NO.136 DongTeng Lake Street Tianjin Economic and Technology Development Area,Tainjin,China
Shanghai Dynamic Industrial Co.,Ltd.
website:http://www.shdynamic.com
Contact:86-021 3392 6680
Address:Room 805 Information Tower, No.1403 Minsheng Road, Pudong New Area, Shanghai 200135, P. R. China
website:http://www.u-chemo.com
Contact:+86-21-61558312
Address:Dong Fang Road,
Wuhan Shangrisyn chemicals Technology Co.,Ltd(expird)
Contact:+86-027-84466317 __ +86-15387123698
Address:wuhan - china
Hubei Xiangxi Chemical Industry Co.,Ltd
Contact:+86-710-3454830
Address:No.7, Daqing East Road, Xiangfan City, Hubei Province, China
Doi:10.1021/jo102455q
(2011)Doi:10.1016/j.molstruc.2011.08.020
(2011)Doi:10.1021/ja01855a005
(1941)Doi:10.1016/S0040-4039(00)98816-6
(1990)Doi:10.1246/cl.1983.913
(1983)Doi:10.1246/bcsj.56.1527
(1983)