PREPARATION OF OPTICALLY ACTIVE PHOSPHINE OXIDES BY REGIOSELECTIVE CLEAVAGE OF CYCLIC PHENYLPHOSPHONITE WITH ALKYL HALIDES

DOI: 10.1246/cl.1983.913

Source and publish data:

Chemistry Letters p. 913 - 916 (1983)

Update date:2022-08-05

Topics:

Authors:

Segi, Masahito

Nakamura, Yoshiyuki

Nakajima, Tadashi

Suga, Sohei

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1983.913

The Arbuzov reaction of (2S,4S)-methyl-2-phenyl-1,3,2-dioxaphosphorinane with various alkyl halides gave the diastereomerically pure phosphinates with regioselective cleavage of the primary carbon-oxygen bond.These phosphinates reacted with Grignard reage

Full text of DOI:10.1246/cl.1983.913

Products guided by the article

Product name:(2S,4S)-4-Methyl-2-phenyl-[1,3,2]dioxaphosphinane

Cas No:87248-70-2

R&D Labs maybe for 87248-70-2

Taizhou Sunny Chemical Co.,Ltd

Contact:+86-523-86920899 +86-13951172783

Address:No.11 Xingyuang road, Gaoyong Chemical Industry Park, Gaogang Jiangsu China
Tianjin SPHINX SCIENTIFIC LAB.

Contact:+86-022-66211289

Address:Tianda high-tech Park. No.80,the 4th Avenue
shanghai meicheng chemical co .,ltd(expird)

Contact:+86-21-50677091

Address:Room 302, Building 7, No.1000, Jinhai Road
Nanjing Chemipioneer Pharma&Tech Co.,Ltd

website:http://www.chemipioneer.com.cn

Contact:+86-25-52685700

Address:Room 305，A Block，Biological-Medicine Building，Business Start-up Center，Xin-ke 1st Road, High-tech development zone，Nanjing city，Jiangsu Province, China

Relevant to this article

Doi:10.1080/07315724.2002.10719246
(1944)
Design and synthesis of 6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid derivatives as PPARγ activators

Doi:10.1016/j.bmcl.2007.05.081
(2007)
Discovery of Novel Small-Molecule Inhibitors of NF-κB Signaling with Antiinflammatory and Anticancer Properties

Doi:10.1021/acs.jmedchem.7b01557
(2018)
Synthesis of 2,5-dihydrobenzo[b]oxepins and 5,6-dihydro-2H-benzo[b]oxocines based on [3+3] cyclizations of 1,3-bis(silyl enol ethers)

Doi:10.1016/j.tet.2007.05.056
(2007)
Intramolecular cycloaddition of O-tert-butyldimethylsilyloximes in the presence of BF₃-OEt₂

Doi:10.1021/jo051652e
(2005)
Activated nitriles in heterocyclic synthesis. A novel synthesis of pyrazolo[1,5-a]pyrimidines and pyrano[2,3-c]pyrazoles

Doi:10.1002/jhet.5570200331
(1983)

Article Doi