SELECTIVITY IN THE LACTONE FORMATION VIA C-H INSERTION REACTION OF DIAZOMALONATES

Article abstract of DOI:10.1016/S0040-4039(00)94420-4

Rhodium(II)-acetate mediated intramolecular C-H insertation reactions of alkyl methyl diazomalonates result in the formation of β- and γ-lactones.The selectivity depends on both the substitution pattern of insertion centers and the conformational bias of metallocarbenes.