
Journal of Medicinal Chemistry p. 3025 - 3033 (1995)
Update date:2022-09-26
Topics:
Arai
Ashizawa
Gomi
Kono
Saito
Kasai
A series of 6-demethylmitomycins and 6-demethyl-6-halomitomycins having various mitomycin skeletons were synthesized, taking into account the electronic effect toward the quinone moiety and the partition coefficients. Treatment of enones 15 and 16 with se
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