O-aryl phosphoramidites: Synthesis, reactivity and evaluation of their use for solid-phase synthesis of oligonucleotides

Article abstract of DOI:10.1016/S0040-4020(01)81356-9

Deoxymicleoside 3′-O-arylphosphoramidites were studied as synthons for preparing natural and modified intenucleotide linkages. Of the various aryl derivatives examined, the 3′-O-phenylphosphoramidite was found to be the most attractive. It reacted with hi