Pig Liver Esterase Catalyzed Hydrolyses of Racemic α-Substituted α-Hydroxy Esters

DOI: 10.1021/jo00310a020

Source and publish data:

Journal of Organic Chemistry p. 5878 - 5881 (1990)

Update date:2022-09-26

Topics:

Authors:

Moorlag, Henk

Kellogg, Richard M.

Kloosterman, Marcel

Kaptein, Bernard

Kamphuis, Johan

Schoemaker, Hans E.

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Article abstract of DOI:10.1021/jo00310a020

Pig liver esterase catalyzed hydrolyses of some α-substituted α-hydroxy esters give product acids and recovered esters in 9-94percent enantiomeric excess.The observed enantiomeric selectivity could be rationalized using a recently proposed active site mod

Full text of DOI:10.1021/jo00310a020

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