Journal of Medicinal Chemistry p. 1292 - 1296 (1991)
Update date:2022-08-02
Topics:
Portoghese, P. S.
Garzon-Aburbeh, A.
Nagase, H.
Lin, C.-E.
Takemori, A. E.
The thiophene 2 and pyran 3 analogue of the κ-selective opioid antagonist norbinaltorphimine (1a, norBNI) were synthesized and tested in an effort to determine the contribution of the spacer to the interaction of bivalent ligands at different opioid recep
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