Zr(O-t-Bu)4, an Efficient and Convenient Basic Reagent in Organic Synthesis. Utilization in Cross and Intramolecular Aldol Reactions

Article abstract of DOI:10.1021/jo00306a003

Zu(O-t-Bu)4 has been found to be a mild basic reagent that can be utilized in cross aldol reactions and intramolecular aldol reactions, in which the use of usual metal enolates such as Li enolate and Cp2ZrCl enolate give unsatisfactory results (2-cyclopentenone -> 5, 7 -> 8, and 13 -> 14).