Synthesis and antiarrhythmic activity of 2,5-disubstituted 2,3-dihydro-1,2,5-benzothiadiazepin-4(5H)-one 1,1-dioxides.

DOI: 10.1248/cpb.40.2442

Source and publish data:

Chemical and pharmaceutical bulletin p. 2442 - 2447 (1992)

Update date:2022-09-26

Topics:

Authors:

Ogawa Ogawa

Matsushita

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Article abstract of DOI:10.1248/cpb.40.2442

A series of 2,5-disubstituted 2,3-dihydro-1,2,5-benzothiadiazepin-4(5H)-one 1,1-dioxide derivatives were prepared and evaluated for the antiarrhythmic effect on ouabain-induced arrhythmias in guinea pigs. Most of the synthesized compounds showed the antia

Full text of DOI:10.1248/cpb.40.2442

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