α-FLUORO- AND α,α-DIFLUOROALKANALS BY SUBSTITUTION OF VICINAL BROMOFLUOROALKANES AND SUBSEQUENT PUMMERER REARRANGEMENT

Article abstract of DOI:10.1016/S0040-4020(01)86763-6

2-Fluoro- or 2,2-difluoro-1-bromoalkanes readily ondergo nucleophilic substitution by sodium thiophenolate to give 2-fluoro- or 2,2-difluoroalkyl phenyl sulfides (1a-1c).The latter may be oxidized to the corresponding sulfoxides (2a-2c).Heating with aceti