A divergent route to nojirimycin analogues from L-serinal and 2-acetylthiazole

DOI: 10.1039/C39900000854

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 854 - 856 (1990)

Update date:2022-08-03

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Authors:

Dondoni, Alessandro

Fantin, Giancarlo

Fogagnolo, Marco

Merino, Pedro

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Article abstract of DOI:10.1039/C39900000854

A five-step synthesis of O,N-protected (+)-3-deoxynojirimycin (7a) and (+)-3-deoxymannojirimycin (7b) from N-Boc L-serinal acetonide (1) employing 2-acetylthiazole (2) as a masked α-hydroxypropanal β-anion synthon is described.

Full text of DOI:10.1039/C39900000854

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