
Journal of Medicinal Chemistry p. 2892 - 2899 (1990)
Update date:2022-08-05
Topics:
Ellingboe
Alessi
Millen
Sredy
King
Prusiewicz
Guzzo
VanEngen
Bagli
Pyrimidineacetic acids and (pyrimidinyloxy)acetic acids were synthesized by alkylation, with methyl bromoacetate or tert-butyl bromoacetate as alkylating agents. Alkylation reaction at the nitrogen or oxygen atom for different substrates was found to be s
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