A Convenient Enantioselective Synthesis of trans-2-Aryloxycyclohexan-1-ols Using Pig Liver Acetone Powder (PLAP) as Biocatalyst

DOI: 10.1016/0957-4166(95)00029-O

Source and publish data:

Tetrahedron Asymmetry p. 439 - 454 (1995)

Update date:2022-08-03

Topics:

Authors:

Basavaiah, Deevi

Krishna, Peddinti Rama

Bharathi, Tirumala K.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0957-4166(95)00029-O

Pig liver acetone powder (PLAP) has been used as a biocatalyst for enantioselective hydrolysis of racemic trans-1-acetoxy-2-aryloxycyclohexanes to produce the resulting (R,R)-2-aryloxycyclohexan-1-ols upto >99percent enantiomeric purities. (R,R)-Selectivity in this hydrolysis of racemic trans-2-aryloxycyclohexyl acetates was explained on the basis of Jones' three dimensional active site-model.

Full text of DOI:10.1016/0957-4166(95)00029-O

Products guided by the article

Product name:(+/-)-trans-1-acetoxy-2-(2-methoxyphenoxy)cyclohexane

Cas No:130336-27-5

R&D Labs maybe for 130336-27-5

Hubei Danao Pharmaceutical Co.,Ltd.

website:http://www.danaopharm.com

Contact:+86-719-5251167

Address:Fandan Road,Danjiangkou,Hubei
Nanjing Norris Pharm Technology Co., Ltd.

Contact:+86-13901585132

Address:2 Qiande Road, Jiangning sciencepark Hi-Tech Zone, Nanjing, P.R.China
Jinan Jiaquan Chemical Co.,Ltd

Contact:+86-531-62318366

Address:Room 502 of Yidonghuayuan No.601 Huaxin Road Licheng District Jinan China
Taizhou Elitechemie MediPharma Technology Co.,Ltd.

Contact:+86-523-86810021

Address:Building G14,NO.1 Avenue,China Medical City, Taizhou, Jiangsu,China
Changzhou BaoKang Pharmaceutical & Chemical Co., Ltd

Contact:(86) 519-88782201 88784080 88785278

Address:Henglin town, changzhou,Jiangsu

Relevant to this article

Stereoselective Hydrogenation via Dynamic Kinetic Resolution

Doi:10.1021/ja00207a038
(1989)
Detection of alkyl, alkoxyl, and alkyperoxyl radicals from the thermolysis of azobis(isobutyronitrile) by ESR/spin trapping. Evidence for double spin adducts from liquid-phase chromatography and mass spectroscopy

Doi:10.1021/ja00179a010
(1990)
Synthesis and biological evaluation of 4-styrylcoumarin derivatives as inhibitors of TNF-α and IL-6 with anti-tubercular activity

Doi:10.1016/j.bmcl.2011.02.016
(2011)
NEW STRATEGY FOR THE CONSTRUCTION OF CARBAPENEMS. TOTAL SYNTHESIS OF 6-epi PS-5 AND PS-5

Doi:10.1016/S0040-4039(00)94734-8
(1990)
Five-membered 2,3-dioxo heterocycles: LXXIV. Recyclization of 3-aroylpyrrolo[1,2-a]quinoxaline-1,2,4(5H)-triones by the action of benzohydrazides. Crystalline and molecular structure of N-[2,4-dihydroxy-5-oxo- 3-(3-oxo-3,4-dihydroquinoxalin-2-yl)-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl] benzamide

Doi:10.1134/S107042801103016X
(2011)
Regioselective N-alkylation of (2-chloroquinolin-3-yl) methanol with N-heterocyclic compounds using the Mitsunobu reagent

Doi:10.2478/s11696-011-0018-1
(2011)

Article Doi