Synthetic Studies on (-)-Tetrodotoxin (3) Nitrogenation through Overman Rearrangement and Guanidine Ring Formation

DOI: 10.1016/S0040-4039(00)89056-5

Source and publish data:

Tetrahedron Letters p. 3327 - 3330 (1990)

Update date:2022-08-05

Topics:

Authors:

Isobe, Minoru

Fukuda, Yoshio

Nishikawa, Toshio

Chabert, Philippe

Kawai, Takatoshi

Goto, Toshio

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Article abstract of DOI:10.1016/S0040-4039(00)89056-5

The guanidinium part of tetrodotoxin was synthesized from a sugar derivative, levoglucosenone, in optically active form via Overman rearrangement as key step.

Full text of DOI:10.1016/S0040-4039(00)89056-5

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