Synthetic Studies on (-)-Tetrodotoxin (3) Nitrogenation through Overman Rearrangement and Guanidine Ring Formation

DOI: 10.1016/S0040-4039(00)89056-5

Source and publish data:

Tetrahedron Letters p. 3327 - 3330 (1990)

Update date:2022-08-05

Topics:

Authors:

Isobe, Minoru

Fukuda, Yoshio

Nishikawa, Toshio

Chabert, Philippe

Kawai, Takatoshi

Goto, Toshio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)89056-5

The guanidinium part of tetrodotoxin was synthesized from a sugar derivative, levoglucosenone, in optically active form via Overman rearrangement as key step.

Full text of DOI:10.1016/S0040-4039(00)89056-5

Products guided by the article

Product name:2,2,2-Trichloro-acetimidic acid 2-cyclohexylidene-ethyl ester

Cas No:130427-40-6

R&D Labs maybe for 130427-40-6

Luojiang Chenming Biological Products Co

Contact:+86 15000297032

Address:GROUP NO.4, HE SHENG VILLAGE, PANLONG TOWN,
Tianjin Ingenochem Technology Co.,Ltd

Contact:+86-22-23677060

Address:Hitech Green Industry Park K2-9-602, Nankai district
Zhangjiagang Methese Composite Material Co.,

Contact:0512-85428658

Address:Shazhou Lake Technological Innovation Park,Zhangjiagang City,Jiangsu Province,China
Shanghai Collins & Paulson Pharmaceuticals Co., Ltd.

Contact:15201714675

Address:Room A647-18, Building No. 2, 351 Guoshoujing Road, Shanghai Free Trade Zone
Xuzhou Tianrun Chemical Co.,Ltd

website:http://www.tianrunchem.cn

Contact:86-516-83832636

Address:fuxing road

Relevant to this article

One-Pot synthesis of sulfonamides from primary and secondary amine derived sulfonate salts using cyanuric chloride

Doi:10.1055/s-0029-1217020
(2009)
Asymmetric Michael addition of nitrobenzyl pyridines to enals via iminium catalysis

Doi:10.1055/s-0030-1259518
(2011)
Doi:10.1021/jo01347a031
(1966)
New methods for the synthesis of fluoroolefins via the palladium catalyzed cross-coupling reaction of 1-fluorovinyl halides with organoboranes and organostannanes

Doi:10.1016/S0022-1139(99)00172-4
(2000)
Fe-Catalyzed Aerobic Oxidative C-CN Bond Cleavage of Arylacetonitriles Leading to Various Esters

Doi:10.1021/acs.joc.6b01594
(2016)
An efficient and mild entry to 1,4-dicarbonyl compounds via photochemical addition of acyl radical to electron-deficient olefins

Doi:10.1016/S0040-4039(00)89026-7
(1990)

Article Doi