Asymmetric Isopropylation of Steroidal 24-Aldehydes for the Synthesis of 24(R)-Hydroxycholesterol

DOI: 10.1016/0957-4166(95)00073-X

Source and publish data:

Tetrahedron Asymmetry p. 767 - 778 (1995)

Update date:2022-08-02

Topics:

Authors:

Okamoto, Makoto

Tabe, Masayasu

Fujii, Takao

Tanaka, Toshio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0957-4166(95)00073-X

The chiral β-amino alcohols-catalyzed addition of diisopropylzinc to steroidal 24-aldehydes successfully provided 24(R)-hydroxycholesterols in good yields with high diastereoselectivities, which are synthetic intermediates of 1α-24(R)-dihydroxyvitamin D3

Full text of DOI:10.1016/0957-4166(95)00073-X

Products guided by the article

Product name:24-(R)-hydroxycholesterol 3-(O)-tert-butyldimethylsilyl ether

Cas No:130474-14-5

R&D Labs maybe for 130474-14-5

Changsha Huajing Powdery Material Technological Co., Ltd.

Contact:86-731-88879686

Address:Building 2, West Garden, Main Campus of Central South University, Changsha, Hunan Province, China
Shandong General Materials Co.,Ltd（Shandong Aoertong Chemical Co., Ltd）

Contact:86-531-88072280

Address:No. 1825 Hualong Road, Licheng District, Jinan, Shandong, China
Shenyang Xingzhenghe Chemical Co., Ltd.

Contact:024-23509232

Address:No. 33, Naner Road, Heping Dist.
Improve Medical Technology(Nanxiong) Co., Ltd

Contact:86-751-3836997

Address:No.33, Pingan First Road, Fine Chemical Industry Base, Nanxiong City, Shaoguan, Guangdong, China
Tianjin Emulsion Science&Technology Development Co.,Ltd

Contact:13901380442

Address:Vake Garden New Town New Yi Bai Road Beichen District Tianjin,China

Relevant to this article

Unusual reactions of amino acid derivatives: N-nitrooxazolidones and N-nitroamino acids

Doi:10.1021/ja00181a074
(1990)
Benzoquinone and naphthoquinone based redox-active labels for electrochemical detection of modified oligonucleotides on Au electrodes

Doi:10.1016/j.tetlet.2015.12.035
(2016)
Organophosphazenes. 25. The synthesis and electrochemistry of the dicobalt hexacarbonyl complexes of phenylethynylcyclophosphazenes

Doi:10.1139/v02-138
(2002)
Preparation of aliphatic ketones through a ruthenium-catalyzed tandem cross-metathesis/allylic alcohol isomerization

Doi:10.1021/ol060918g
(2006)
The Synthesis of Optically Pure Epoxyalkyl β-D-Glucosides and β-Cellobiosides as Active-Site Directed Inhibitors of Some β-Glucan Hydrolases

Doi:10.1071/CH9901391
(1990)
Chlorination of oximes with aqueous H₂O₂/HCl system: Facile synthesis of gem-chloronitroso- and gem-chloronitroalkanes, gem-chloronitroso- and gem-chloronitrocycloalkanes

Doi:10.1055/s-2006-950304
(2006)

Article Doi