Enantiocontrolled synthesis of chiral propane-1,3-diol derivatives possessing fluorinated quaternary stereogenic centers

DOI: 10.1016/0957-4166(94)80054-5

Source and publish data:

Tetrahedron Asymmetry p. 1041 - 1050 (1994)

Update date:2022-08-03

Topics:

Authors:

Ihara Ihara

Kawabuchi

Tokunaga

Fukumoto

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Article abstract of DOI:10.1016/0957-4166(94)80054-5

A general method for the preparation of chiral propane-1,3-diol derivatives possessing fluorinated quaternary stereogenic centers was established as follows. The diastereoselective alkylation of (1R,3R,4S)-8-phenylmenthyl hydrogen fluoromalonate 9, follow

Full text of DOI:10.1016/0957-4166(94)80054-5

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