Synthesis of the C10-C34 segment of the immunosuppressant FK506

DOI: 10.1016/S0040-4039(00)89045-0

Source and publish data:

Tetrahedron Letters p. 3287 - 3290 (1990)

Update date:2022-08-03

Topics:

Authors:

Sih Sih

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)89045-0

The biocatalytic strategy used in the synthesis of the C₂₀-C₃₄ fragment, 2, and the methodology for its attachment to 1 to generate the C₁₀-C₃₄ moiety of FK506 is disclosed.

Full text of DOI:10.1016/S0040-4039(00)89045-0

Products guided by the article

Product name:(E)-3-Acetoxy-5-((1R,3R,4R)-4-acetoxy-3-methoxy-cyclohexyl)-2,4-dimethyl-pent-4-enoic acid methyl ester

Cas No:130677-98-4

R&D Labs maybe for 130677-98-4

SNC | GOOD FORTUNE

Contact:0086-22-2822 1962 / 2822 1963

Address:B-808, No. 1, North-South Street, Hexi District,
Hopechem Co., Ltd.

Contact:+86-20-38011066

Address:3510, Diwang Commercial Center, 5002 Shennan Rd, Shenzhen, P.R.China
A.M FOOD CHEMICAL CO., LIMITED

Contact:86-531-87100375

Address:20Floor，Bblock，1Building，pharma-valley，Jinan，China
Xi'an Tizan Tech & Industry Co., Ltd.

Contact:86-18629066522

Address:C3009 TANG FENG INTERNATIONAL PLAZA, NO.18 FENGHUI NAN ROAD, XI'AN HIGH TECH ZONE, 710075 CHINA.
Chen jie

Contact:027-87677569

Address:Room 2203, yujingmingmen Buidling One, xiongchu Road, wuhan city, hubei province, China

Relevant to this article

Facile preparation of bicyclo[2.2.2]octenone derivatives via Diels-Alder cycloadditions of in situ-generated masked o-benzoquinones

Doi:10.1016/j.tet.2011.03.018
(2011)
Folic Acid Analogues Lacking the 2-Carbon Are Substrates for Folylpolyglutamate Synthetase and Inhibit Cell Growth

Doi:10.1021/jm00105a070
(1991)
Alternative Protocol for the Synthesis of Symmetrical Dibenzyl Diselenides and Disulfides

Doi:10.1055/s-0035-1561579
(2016)
Preparation of dehydroalanine peptides from bis-(2,2,2-trichloroethyl) and diphenyl phosphonoserine derivatives

Doi:10.1016/S0040-4039(00)98047-X
(1990)
Strict size specificity in colorimetric anion detection based on poly(phenylacetylene) receptor bearing second generation lysine dendrons

Doi:10.1021/ma200710r
(2011)
Synthesis and biochemical analysis of 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro- N-hydroxy-octanediamides as inhibitors of human histone deacetylases

Doi:10.1016/j.bmc.2011.11.041
(2012)

Article Doi