REMOTE ACYCLIC STEREOCONTROL; CHIRAL SYNTHESIS OF (+)-PEDAMIDE

Article abstract of DOI:10.1016/0040-4020(84)80017-4

Synthesis of optically active pedamide (3), one of the tetrahydropyran moieties of the potent insect poison pederine (1), has been accomplished through a new, remote controlled asymmetric reduction of a ketone as key step.