CHIRAL SYNTHESIS OF Z-2-BUTYLIDENECYCLOHEXAN-1-OL AND -1-YL PHENYLSULPHIDE FROM OPTICALLY ACTIVE PHOSPHINE OXIDES

Article abstract of DOI:10.1016/S0040-4039(00)94688-4

Optically active butyl(ortho-methoxyphenyl)phenylphosphine oxide is used to create three new chiral carbon atoms as a carbon framework is built up by stereoselective electrophilic attack on a cyclic allylic phosphine oxide.Elimination of the chiral auxili