Journal of Organic Chemistry p. 6502 - 6508 (1992)
Update date:2022-08-03
Topics:
Morris, Joel
Wishka, Donn G.
Fang, Yue
A novel method for the synthesis of antiplatelet 2-aminochromones making use of the reaction of 2'-hydroxyacetophenone-BF2 complexes with phosgeniminium chlorides has been developed.Aqueous hydrolysis of the intermediate β-chlorovinylogous amide-BF2 complex affords the 2-aminochromone in good yield, without the need for chromatographic purification.
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(1990)Doi:10.1016/S0960-894X(98)00422-3
(1998)Doi:10.1016/S0022-328X(00)92660-3
(1968)Doi:10.1021/jo980704f
(1998)Doi:10.1021/jo981380y
(1998)Doi:10.1016/S0040-4039(98)01668-2
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