Synthesis of sialyl Lewis X mimetics using the Ugi four-component reaction

DOI: 10.1016/S0960-894X(98)00422-3

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2333 - 2338 (1998)

Update date:2022-08-03

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Authors:

Tsai, Chung-Ying

Park, William K. C.

Weitz-Schmidt, Gabriele

Ernst, Beat

Wong, Chi-Huey

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Article abstract of DOI:10.1016/S0960-894X(98)00422-3

Application of the Ugi four-component condensation to rapidly synthesize a library of glycopeptide mimics of the tetrasaccharide SLe(x) as inhibitors of E- and P-selectin, and to study the effect of varied functionality in mimics on the inhibition is desc

Full text of DOI:10.1016/S0960-894X(98)00422-3

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