TOTAL SYNTHESIS OF ESCHERICHIA COLI LIPID A

DOI: 10.1016/S0040-4039(00)98548-4

Source and publish data:

Tetrahedron Letters p. 1545 - 1548 (1985)

Update date:2022-09-26

Topics:

Authors:

Imoto, Masahiro

Yoshimura, Hiroyuki

Sakaguchi, Nobuki

Kusumoto, Shoichi

Shiba, Tetsuo

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Article abstract of DOI:10.1016/S0040-4039(00)98548-4

The first total synthesis of E. coli lipid A (1) is described.The synthetic compound was identical with a natural specimen and exhibited the full endotoxic activity.It was thus conclusively proved by this chemical synthesis that lipid A is the active prin

Full text of DOI:10.1016/S0040-4039(00)98548-4

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