Tetrahedron Letters p. 1545 - 1548 (1985)
Update date:2022-09-26
Topics:
Imoto, Masahiro
Yoshimura, Hiroyuki
Sakaguchi, Nobuki
Kusumoto, Shoichi
Shiba, Tetsuo
The first total synthesis of E. coli lipid A (1) is described.The synthetic compound was identical with a natural specimen and exhibited the full endotoxic activity.It was thus conclusively proved by this chemical synthesis that lipid A is the active prin
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