Journal of Medicinal Chemistry p. 574 - 579 (1991)
Update date:2022-09-26
Topics:
Rosowsky, Andre
Bader, Henry
Freisheim, James H.
The heretofore unknown γ-(m-carboxylanilide) and γ-(m-boronoanilide) derivatives of methotrexate (MTX) and γ-(m-carboxyanilide) derivatives of aminopterin (AMT) were prepared and tested as inhibitors of dihydrofolate reductase (DHFR) and as inhibitors of
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