European Journal of Medicinal Chemistry p. 441 - 447 (1990)
Update date:2022-08-02
Topics:
Aatif, A.
Mouaddib, A.
Carre, MC.
Jamart-Gregoire, B.
Geoffroy, P.
et al.
Two series of new benzocyclobutenic and benzocyclenic compounds were synthesized and tested for bronchospasmolytic effects.Theophylline was used as reference.Compound 1b was found to be 12.6 to 15.8-fold more potent in vitro than theophylline and devoid of antagonistic effects towards adenosine.
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