New experimental conditions for tandem hydroalumination/Cu-catalyzed asymmetric conjugate additions to β-substituted cyclic enones

Article abstract of DOI:10.1021/ol200898c

Readily available alkenylalanes, arising from hydroalumination of unprotected terminal alkynes, have been directly employed for the copper-catalyzed asymmetric conjugate addition (ACA) to β-substituted cyclic enones. The desired products, containing a qua