
Journal of medicinal chemistry p. 140 - 151 (1991)
Update date:2022-09-26
Topics:
Swain
Baker
Kneen
Moseley
Saunders
Seward
Stevenson
Beer
Stanton
Watling
The synthesis and biochemical evaluation of a series of indole oxadiazole 5-HT3 antagonists are described. The key pharmacophoric elements have been defined as a basic nitrogen, a linking group capable of H-bonding interactions, and an aromatic moiety. Th
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