Chemically Stable, Lipophilic Prodrugs of Phosphoramide Mustard as Potential Anticancer Agents

DOI: 10.1021/jm00106a018

Source and publish data:

Journal of Medicinal Chemistry p. 588 - 592 (1991)

Update date:2022-09-26

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Authors:

Kwon, Chul-Hoon

Moon, Ki-Young

Baturay, Nesrine

Shirota, Frances N.

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Article abstract of DOI:10.1021/jm00106a018

Benzyl phosphoramide mustard (3), 2,4-difluorobenzyl phosphoramide mustard (4), and methyl phosphoramide mustard (5) were examined as lipophilic, chemically stable prodrugs of phosphoramide mustard (2).These phosphorodiamidic esters are designed to underg

Full text of DOI:10.1021/jm00106a018

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