Development of an N-sulfinyl prolinamide for the asymmetric aldol reaction

DOI: 10.1016/j.tet.2011.03.030

Source and publish data:

Tetrahedron p. 4412 - 4416 (2011)

Update date:2022-07-29

Topics:

Authors:

Robak, Maryann T.

Herbage, Melissa A.

Ellman, Jonathan A.

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Article abstract of DOI:10.1016/j.tet.2011.03.030

A new class of organocatalysts is reported that incorporates an N-sulfinyl amide in place of the carboxylic acid of proline to serve as a hydrogen bond donor, chiral directing group, and solubilizing element. The successful application of this type of cat

Full text of DOI:10.1016/j.tet.2011.03.030

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