Organic and Biomolecular Chemistry p. 4873 - 4881 (2011)
Update date:2022-07-29
Topics:
Rannoux, Claire
Roussi, Fanny
Martin, Marie-Therese
Gueritte, Franoise
Hybrids of vinblastine and phomopsin, designed by a molecular modelling study, were elaborated in order to target tubulin. The key step of the synthesis (fragmentation and insertion of vindoline) was mediated by an internal N-carboxyanhydride (or O-acylca
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