Enantiomerically Pure Acetals in Organic Synthesis. 1. Chromatographic Separability of Furanoside and Pyranoside Acetals Derived from α-Hydroxy Esters

Article abstract of DOI:10.1021/jo00003a034

A general chromatographic separation of diastereomeric furanoside and pyranoside acetals derived from α-hydroxy esters is described.Application of this separation methodology is made to rapid syntheses of the diastereomers of (S)-methyl lactyl 4-deoxy-β-erythro-pentopyranoside.