Tetrahedron Letters p. 4845 - 4848 (1990)
Update date:2022-08-05
Topics:
Goulet, Mark T.
Boger, Joshua
The degradation of rapamycin, a tricarbonyl containing macrolide similar in structure to the potent immunosuppressant FK-506, is described.Three principal fragments are obtained in this process that should have utility in the semi-synthesis of FK-506 and
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